FBG says: Bad matchup. The Colts rushing offense had a bye week at the right time as their lead running back Marlon Mack was struggling through an ankle injury for the past couple of weeks. In their Week 5 outing, however, Mack showed minimal signs of injury as he ran a whopping 29 times for 132 yards. The Colts like to run their offense through Mack, and they will continue to do so when game scripts allow it. While Nyheim Hines works in on passing downs while Jordan Wilkins will grab a goal-line carry here and there, Mack will remain the focal point of this rushing offense that has afforded him 20 or more carries in three of five games. The Indianapolis offensive line has been a top-tier unit led by impressive play from second-year guard Quenton Nelson. They will have their hands full this week, but this offensive line puts Mack in a great position to continue his success as a rusher.
The Texans run defense has been one of the best in football this season, holding opposing running backs to just 73 rushing yards per game (seventh-fewest) and only two rushing touchdowns through six games. If not for their porous coverage of pass-catching running backs, this group would really be limiting the fantasy output of opposing running backs. Much of this credit goes on the shoulders of D.J. Reader, who has been one of the top nose tackles in football to start the season. Reader should pose a big challenge to the interior of this Colts offensive line. Rookie Charles Omenihu is also having a great start to the season, but he simply isn't seeing many snaps against the run despite looking like one of the better interior linemen--much better than Angelo Blackson, who is seeing most snaps next to Reader. Both J.J. Watt and Whitney Mercilus will continue to be challenging matchups for opposing offensive tackles, while Zach Cunningham has shown to be a top-notch run-defending linebacker. This group should make it tough on Colts rushers despite the stout Colts offensive line that matches up relatively well with this Texans defensive line in the trenches.