Preseason projections for
| Rank | Name | Tm/Bye | Age | G | Rsh | Yd | Y/R | TD | Rec | Yd | TD | FantPt |
| 1 | Darren Sproles | PHI/10 | 36 | 12.0 | 25.0 | 100 | 4.0 | 0.5 | 20.0 | 160 | 1.1 | 35.60 |
| 2 | Frank Gore | BUF/6 | 36 | 14.2 | 95.0 | 371 | 3.9 | 2.4 | 18.0 | 148 | 1.2 | 73.50 |
| 3 | Adrian Peterson | WAS/10 | 34 | 14.4 | 145.0 | 592 | 4.1 | 4.7 | 14.0 | 118 | 0.9 | 104.60 |
| 4 | LeSean McCoy | KC/12 | 31 | 14.0 | 100.0 | 405 | 4.1 | 3.5 | 17.0 | 122 | 1.0 | 79.70 |
| 5 | Bilal Powell | NYJ/4 | 31 | 13.0 | 40.0 | 160 | 4.0 | 0.6 | 7.0 | 55 | 0.2 | 26.30 |
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