| Player | TM | Wk11 | Wk12 | Wk13 | Wk14 | Wk15 | Wk16 | Wk17 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Christian McCaffrey | SF | - | 11 | 10 | 7 | 11 | 13 | 1 | 124 | 7.8 | 7.8 | 107 | 867 | 8.1 | 6 | 86.3 |
| Saquon Barkley | PHI | 3 | 8 | 4 | 5 | 10 | 7 | 8 | 121 | 7.6 | 7.6 | 91 | 721 | 7.9 | 4 | 75.2 |
| Alvin Kamara | NO | 1 | 1 | 11 | 6 | 9 | 6 | dnp | 105 | 6.6 | 7.0 | 81 | 709 | 8.8 | 4 | 77.1 |
| Tarik Cohen | CAR | 4 | 8 | 14 | 4 | 6 | 1 | 3 | 89 | 5.6 | 5.6 | 71 | 725 | 10.2 | 5 | 79.8 |
| Nyheim Hines | CLE | - | 2 | 9 | 5 | 6 | 5 | 5 | 81 | 5.1 | 5.1 | 63 | 425 | 6.7 | 2 | 77.8 |