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Week 1 vs. JAX
Receiving: 10 / 162 / 1 on 14 targets
Wayne took rookie Derek Cox to school all day, and he could have easily had 200 yards and multiple TDs if not for the one good play in coverage Cox did make, sniffing out a goal line fade and intercepting it. Wayne had a long TD, and another long catch from Manning, in addition to lots of short targets to keep the chains moving. Manning hit him deep on another play in the second half, but Wayne couldn't keep possession of the ball when he hit the ground. Wayne is clearly the biggest beneficiary of Gonzalez' injury - most of the game was played without Gonzalez, and it's no coincidence that Wayne got big target, catch and yard numbers.
Week 2 vs. MIA
Receiving: 3 / 37 / 0 on 6 targets
Wayne was covered pretty well by rookie Sean Smith, although if the Colts had gotten the ball more, he would have still had a solid fantasy night. He showed that telepathy with Manning on a back shoulder throw, and he got a few targets early, but it was a very quiet night for Manning as he took a back seat to Dallas Clark.
Week 3 vs. ARI
Receiving: 7 / 126 / 1 on 9 targets
Wayne had a ho-hum studly night, reeling in one-handed TDs and deep balls, and working the outside of the field with ease, much to the frustration of the Cardinal DBs. Wayne's hands were ridiculously good, and like Manning, it seemed like he was doing his job without thinking.
Week 4 vs. SEA
Receiving: 6 / 74 / 1 on 11 targets
Reggie Wayne was not targeted once in the first quarter.Then just when you start to forget about him, boom, he picks up his first reception, a 5 yard TD in heavy traffic. After that, Manning found him more often, but never for the long gains we are used to seeing. With the other receiving options excelling, there was no need.
Week 5 vs. TEN
Receiving: 6 / 60 / 1 on 8 targets
The wily vet made the most of his opportunities going 6 for 60 and a TD. Wayne was mostly double-teamed so Manning looked to his other targets more frequently on Sunday night however he caught a key 4th down TD catch on a well designed pick play in the 1st quarter. This help set the tone for the rest of the game for the Colts offense. Wayne had a rare drop in the 4th quarter of a TD pass from Manning, but the game was out of reach by that point.
Week 7 vs. STL
Receiving: 7 / 83 / 1 on 9 targets
Wayne opened the game quickly, getting plenty of targets and catches in the opening minutes. Wayne dominated the first drive, catching four balls for a combined 61 yards including his long for the day of 25 yards. Wayne finished off the drive with a short catch for the first Colts touchdown of the day. Wayne did tweak his groin and missed some of the rest of the first half, but he was able to return to action after halftime to collect some additional grabs. Wayne could have topped 100 yards if not for the Colts letting the backups play after the game was well in hand.
Week 8 vs. SF
Receiving: 12 / 147 / 1 on 20 targets
Manning relied on Wayne heavily the entire game and he did not disappoint.
Wayne was covered pretty tightly and so the Colts used him often, and uncharacteristically, on shorter routes. On a couple of deep patterns, he was overthrown and the pass was defended. This was typically what happened when Manning tried to hit him for anything beyond ten yards Wayne did manage to get his yards, though, much of them after the catch. His touchdown was a 22 yard pass from Addai, who found him wide open in the end zone.
Week 9 vs. HOU
Passing: 0 - 1, 0 yards, 0 TD, 1 INT
Receiving: 8 / 64 / 0 on 9 targets
Wayne had a game that is likely to be underappreciated by fantasy owners. He finished the day with 64 yards but had 8 receptions, most of which came in the 7-11 yard range. Wayne was jammed often at the line of scrimmage the Texans always had a safety shaded to his side of the field to take away deep routes. That said, Wayne still managed to fight through coverages and make a number of "vintage" grabs that remind fans why he and Manning have the most passes/catches together of any active NFL duo. Wayne also provided key blocks on the outside corner on at least 3 of Dallas Clark's catches, allowing Clark to rumble for a few more yards.
Week 10 vs. NE
Receiving: 10 / 126 / 2 on 12 targets
Reggie Wayne started slowly against the Patriots in Week 10 as New England tried to limit him early on, but Wayne and Peyton Manning eventually adjusted. Wayne got on track later in the second quarter as he capped a scoring drive with a nice route to the middle of the end zone for a 20-yard touchdown. Wayne was a perfect 7-for-7 in the second half, gaining 90 of his 126 yards and his second touchdown of the night after intermission. Wayne is a top flight fantasy wide receiver regardless of the defensive team he faces any week.
Week 11 vs. BAL
Receiving: 7 / 89 / 0 on 10 targets
When an elite player like Reggie Wayne is having an elite season, games like these can seem like pedestrian efforts. However Wayne was tremendous yet again in week 11. He continually beat press coverage in his short and intermediate routes and often got loose for a few deeper catches. Wayne was Manning's most targeted receiver again, and finished with solid numbers.
Week 12 vs. HOU
Receiving: 3 / 19 / 1 on 6 targets
Wayne was double-covered much of the game, leading to a modest statline. However, his real effect came on two critical passes --- a deep ball to the left side and a fade in the endzone. Both plays resulted in pass interference calls that set the Colts up for key touchdowns. Wayne did manage to catch 3 balls including a great touchdown grab at the left back corner of the endzone. Peyton Manning's use of Pierre Garcon and Austin Collie limited Reggie Wayne's ability to produce in this game, but it's hard to argue with the team's results.
Week 13 vs. TEN
Receiving: 4 / 48 / 0 on 7 targets
Wayne was basically invisible for much of the game. He was very tightly covered nearly every time he was thrown to. Late in the game, he made the most of his few opportunities, as he was getting open for a change and Manning was able to find him a few times.
Week 14 vs. DEN
Receiving: 4 / 43 / 0 on 7 targets
Reggie Wayne was blanketed by All-Pro cornerback Champ Bailey for most of the game on Sunday, but he did manage to wiggle free on a few routes. With the Broncos refusing to give up the big play, all of Wayne's catches were on short and underneath routes. Manning did try to target Wayne deep a few times, but 2 of his 3 interceptions were on passes intended for Wayne. His biggest play of the day, a 20-yard reception, came in the fourth quarter on the Colts final scoring drive. Wayne hauled in the short pass on the right side of the field, and was able to pick up most of the yardage after the catch until safety Brian Dawkins tackled him downfield.
Week 15 vs. JAX
Receiving: 5 / 132 / 1 on 7 targets
Reggie Wayne started very slowly on the night, catching just one pass for a 22 yard gain in the first half. Wayne made the grab on a skinny post and nearly slipped a tackle and broke off a touchdown run after the catch in the second quarter but he hit the ground instead. Wayne upped his game in the second half as he was open more with the Jaguars covering Dallas Clark more, which opened Wayne up for three grabs in the third quarter and then finally a 65-yard run down the left sideline on which Peyton Manning delivered a 40-yard strike in the air for the touchdown. The long score was Wayne's longest catch of the year.
Week 16 vs. NYJ
Receiving: 3 / 33 / 0 on 7 targets
Wayne came out of the game in the third quarter. He actually played second fiddle to Austin Collie in this one. Wayne's best chance in came in the end zone, but he just couldn't hang on to the ball.
Week 17 vs. BUF
Receiving: 5 / 21 / 0 on 7 targets
Wayne got enough catches to get to 100 on the season, mostly on throws at or behind the line of scrimmage, then he left the game.
Week 19 vs. BAL
Receiving: 8 / 63 / 1 on 11 targets
Wayne was quiet early on during the game; however he became more involved as the game progressed and ended up making the majority of the Colts key offensive plays. He made a terrific effort in scoring the Colts 2nd TD as time expired in the 1st half. On the play, Wayne grabbed a short slant route reception and extended the ball past the goal-line as he was met by the Ravens defenders. Wayne finished the game with a team leading 8 catch on 11 targets.
Week 20 vs. NYJ
Receiving: 3 / 55 / 0 on 5 targets
Wayne caught a pass very early on that epitomized the game for him. He had to comeback to the ball, away from double coverage, and catch it near the turf. The result of this sort of coverage was that Manning went elsewhere, and, finding success with Austin Collie, Pierre Garcon, and Dallas Clark, Wayne played decoy for much of the game. He was targeted once in the end zone, but was overthrown.