NOTE: only players with at least 2 targets per week are shown.
| Player | TM | Wk14 | Wk15 | Wk16 | Wk17 | Wk18 | Wk19 | Wk20 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kyle Juszczyk | SF | 4 | 4 | 5 | 4 | - | - | - | 42 | 2.6 | 3.0 | 33 | 315 | 9.5 | 1 | 78.6 |
| Trent Taylor | SF | 3 | 5 | 4 | 2 | - | - | - | 60 | 3.8 | 4.0 | 43 | 430 | 10.0 | 2 | 71.7 |
| Christian McCaffrey | SF | 4 | 7 | 4 | 8 | - | - | - | 121 | 7.6 | 7.1 | 86 | 752 | 8.7 | 6 | 71.1 |
| George Kittle | SF | 2 | 5 | 3 | 6 | - | - | - | 63 | 3.9 | 4.2 | 43 | 515 | 12.0 | 2 | 68.3 |
| Marqise Lee | SF | 6 | 0 | dnp | dnp | - | - | - | 103 | 6.4 | 6.4 | 59 | 730 | 12.4 | 3 | 57.3 |